In recent times CESM (contrast enhanced spectral mammography) has aroused a growing interest among breast radiologists proving to be a pioneering and very promising new tool in the early diagnosis of breast cancer. Our aim is to provide physicians with a interactive environment to learn and share knowledge and views about CESM in a creative and engaging setting in the beautiful city of Florence. During this 2-days course partecipants will receive notions on CESM acquisition technique, step-bystep imaging interpretation and report writing, as well as additional findings management, focusing on ultrasound (US), tomosynthesis and post- CESM second look ultrasound examinations. Eventually, prone stereotactic tomo-guided bioptic approaches and US-guided biopsies (core biopsy) will be performed on CESM findings to complete the diagnostic procedures. Additionally, trainees will participate in interactive case-based discussions at workstations reviewing some of the most significant examinations drawn from our department database which consists of more than 5000 CESM examinations performed over the last six years.